OSLER, WILLIAM. 1849-1919.


The Principles and Practice of Medicine. New York: D. Appleton and Company, 1905. 8vo (245 x 166 mm). Publisher's red cloth. Bumping to edges of covers and spine ends, dust-soiling to edges of leaves.Provenance: G.R. Butler (pencil inscription).PRESENTATION COPY, numbered "110" on the inserted presentation leaf, inscribed by Osler. "Two states of the sixth edition (1905) were produced. The first contained an added leaf on heavier stock preceding the title page, with the printed note, 'PRESENTATION COPY. This is No.__ of the first 105,000 copies printed ... Some copies of the first state bear the holographic inscription 'Sincerely yours, Wm. Osler' on the supernumerary leaf, apparently for later presentation. The second state may be distinguished by the absence of the presentation page" (Golden, A History of William Osler's The Principles and Practice of Medicine, Montreal). This edition was published in 1905, the same year he was appointed to the Regius Chair of Medicine at Oxford. In his preface he writes, "So many sections have been rewritten, and so many alterations made, that in many respects this is a new book ... I have tried to make the work a reflex of current knowledge in the symptomatology and treatment of disease, based upon the literature and upon our experience at the Medical Clinic of the Johns Hopkins Hospital." Golden & Roland 1399.