LOT 95 Two Typed Letters Signed and one Autograph Letter Signed ("Archibald E. Garrod"), to Walter Bett, two of them regarding J.M.J. Parrot, GARROD, ARCHIBALD EDWARD. 1857-1936.
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GARROD, ARCHIBALD EDWARD. 1857-1936.
Two Typed Letters Signed and one Autograph Letter Signed ("Archibald E. Garrod"), to Walter Bett, two of them regarding J.M.J. Parrot, 4 pp total, 8vo, February 8, and April 19, 1930, and May 19, 1933, different papers, the last with a sticker affixed to the upper corner.Archibald Edward Garrod "established chemical individuality as a paradigm of Mendelian variation. His study, which began around the turn of the 20th century, coincided with the rediscovery of Mendel's laws of inheritance in 1900. He realized that alkaptonuria (black urine disease) behaves like one of Mendel's recessive gene traits, and guessed that people with alkaptonuria have a defective gene that produces a faulty enzyme that interrupts an important metabolic pathway. This was the first recognition of the possibility that genes direct the assembly of enzymes, and more specifically, that each gene codes for one enzyme" (Garrison-Morton 244.1 and 3921).
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